Dandruff is a common scalp condition, which frequently causes psychological distress in those affected. Dandruff is considered to be caused by an interplay of several factors. However, the pathogenesis of dandruff remains under‐investigated, especially with respect to the contribution of the hair follicle. As the hair follicle exhibits unique immune‐modulatory properties, including the creation of an immunoinhibitory, immune‐privileged milieu, we propose a novel hypothesis taking into account the role of the hair follicle. We hypothesize that the changes and imbalance of (...) yeast and bacterial species, along with increasing proinflammatory sebum by‐products, leads to the activation of immune response and inflammation. Hair follicle keratinocytes may then detect these changes in scalp microbiota resulting in the recruitment of leukocytes to the inflammation site. These changes in the scalp skin immune‐microenvironment may impact hair follicle immune privilege status, which opens new avenues into exploring the role of the hair follicle in dandruff pathogenesis. Also see the video abstract here: https://youtu.be/mEZEznCYtNs. (shrink)

Humeanism about laws of nature — the view that the laws reduce to the Humean mosaic — is a popular view, but currently existing versions face powerful objections. The non-supervenience objection, the non-fundamentality objection and the explanatory circularity objection have all been thought to cause problems for the Humean. However, these objections share a guiding thought — they are all based on the idea that there is a certain kind of divergence between the practice of science and the metaphysical picture (...) suggested by Humeanism. -/- I suggest that the Humean can respond to these objections not by rejecting this divergence, but by arguing that is appropriate. In particular the Humean can, in the spirit of Loewer (2012), distinguish between scientific and metaphysical explanation — this is motivated by differing aims of explanation in science and metaphysics. And they can further leverage this into distinctions between scientific and metaphysical fundamentality and scientific and metaphysical possibility. We can use these distinctions to respond to the objections that the Humean faces. (shrink)

Tim Maudlin has influentially argued that Humeanism about laws of nature stands in conflict with quantum mechanics. Specifically Humeanism implies the principle Separability: the complete physical state of a world is determined by the intrinsic physical state of each space-time point. Maudlin argues Separability is violated by the entangled states posited by QM. We argue that Maudlin only establishes that a stronger principle, which we call Strong Separability, is in tension with QM. Separability is not in tension with QM. Moreover, (...) while the Humean requires Separability to capture the core tenets of her view, there's no Humean-specific motivation for accepting Strong Separability. We go on to give a Humean account of entangled states which satisfies Separability. The core idea is that certain quantum states depend upon the Humean mosaic in much the same way as the laws do. In fact, we offer a variant of the Best System account on which the systemization procedure that generates the laws also serves to ground these states. We show how this account works by applying it to the example of Bohmian Mechanics. The 3N-dimensional configuration space, the world particle in it and the wave function on it are part of the best system of the Humean mosaic, which consists of N particles moving in 3-dimensional space. We argue that this account is superior to the Humean account of Bohmian Mechanics defended by Loewer and Albert, which takes the 3N-dimensional space, and its inhabitants, as fundamental. (shrink)

Here is a puzzling phenomenon. Moral theories are typically thought to be necessary. If act utilitarianism is true, for example, then it is necessarily true. However, scientific theories are typically thought to be contingent. If quantum field theory is true, it’s not necessarily true — the world could have been Newtonian. My aim is to explore this discrepancy between domains. -/- In particular, I explore the role of what I call `internality’ intuitions in motivating necessitism about both moral and scientific (...) domains. In effect, these internality intuitions tell against the explanatory role of certain `external’ entities – like moral or scientific principles. I’ll suggest that perhaps these internality intuitions are more compelling in the moral case than the scientific case. If so, this would rationalize the combination of moral necessitism and scientific contingentism. (shrink)

Many moral debunking arguments are driven by the idea that the correlation between our moral beliefs and the moral truths is a big coincidence, given a robustly realist conception of morality.One influential response is that the correlation is not a coincidence because there is a common explainer of our moral beliefs and the moral truths. For example, the reason that I believe that I should feed my child is because feeding my child helps them to survive, and natural selection instills (...) in me beliefs and dispositions that help my children survive since that is conductive to my genes continuing through the generations. Similarly, the reason that it's morally good to feed my child is because it helps them to survive, and survival is morally valuable.But if we look at some cases from scientific practice, and from everyday life, we can see, I argue, why this response fails. A correlation can be coincidental even if there is a common explainer. I give an account of the nature of coincidence that draws upon recent literature on scientific explanation and argue that the correlation between moral belief and moral truth is a coincidence, even given such common explainers. And I use this to defend a certain form of debunking argument. (shrink)

Some properties – like charge – are natural, some – like grue are unnatural. The distinction between natural and unnatural properties is normally taken as primitive. However, Barry Loewer’s Package Deal Account (PDA) aims to provide an reductive account of natural properties, integrated with a reductive account of laws of nature. In addition, the account seems to be able to apply to natural properties at the level of fundamental physics, and higher-level, special science, properties. -/- If the account is successful, (...) then, it looks to be incredibly powerful and attractive. The PDA, however, is somewhat underexplored in the literature. So the first aim of the paper is to understand the PDA better -- to map the connections between naturalness and laws on the traditional BSA and to consider how those connections have to adapted in order to develop different versions of the PDA. -/- The second aim is to start to evaluate different versions of the PDA. In particular, perhaps the most promising version of the PDA construes it as an instance of a larger approach to Humeanism — one that has been very visible in the recent literature — that focuses on the role of 'ideal observers' or 'ideal scientists'. While such an approach might be feasible, I claim, it gets its proponents much less than they were originally hoping for. (shrink)

Humeanism about laws of nature is, roughly, the view that the laws of nature are just patterns, or ways of describing patterns, in the mosaic of events. In this paper I survey some of the (many!) objections that have been raised to Humeanism, considering how the Humean might respond. And I consider how we might make a positive case for Humeanism. The common thread running through all this is that the viability of the Humean view relies on the Humean having (...) an importantly different conception of explanation to the anti-Humean. (shrink)

At the core of the recent debate over moral debunking arguments is a disagreement between explanationist and modalist approaches. Explanationists think that the lack of an explanatory connection between our moral beliefs and the moral truths, given a non-naturalist realist conception of morality, is a reason to reject non-naturalism. Modalists disagree. They say that, given non-naturalism, our beliefs have the appropriate modal features with respect to truth -- in particular they are safe and sensitive -- so there is no problem. (...) -/- There is something of a stand-off here. I argue, though, that by looking at the role explanatory and modal factors have to play in theory choice more generally, and, in particular, by considering the practice of theory choice in science, we can see that the explanationist is right. The lack of an explanatory connection between our moral beliefs and the moral truths is a reason to reject non-naturalist realism about morality. (shrink)

I give an account of what makes an event a coincidence. -/- I start by critically discussing a couple of other approaches to the notion of coincidence -- particularly that of Lando (2017) -- before developing my own view. The central idea of my view is that the correct understanding of coincidences is closely related to our understanding of the correct 'level' or 'grain' of explanation. Coincidences have a kind of explanatory deficiency — if they did not have this deficiency (...) they would not be coincidences. This deficiency, I claim, is the same explanatory deficiency as when we give low-level explanations of special science phenomena. Such explanations are typically too specific and not robust enough. I claim that there is this same badness in purported explanations of coincidences. -/- I cash out this idea sketching an account of explanatory goodness — an account of what makes explanations better or worse -- and using that to give a more precise account of coincidences. (shrink)

There is a tension in our theorizing about laws of nature: our practice of using and reasoning with laws of nature suggests that laws are universal generalizations, but if laws are universal generalizations then we face the problem of explanatory circularity. In this paper I elucidate this tension and show how it motivates a view of laws that I call Minimal Anti-Humeanism. This view says that the laws are the universal generalizations that are not grounded in their instances. I argue (...) that this view has a variety of advantages that could make it attractive to people with both Humean and anti-Humean inclinations. (shrink)

Humean accounts of chance have a problem with undermining futures: they have to accept that some series of events are physically possible and have a nonzero chance but are inconsistent with the chances being what they are. This contradicts basic platitudes about chances (such as those given by Bigelow et al. (1993) and Schaffer (2007)) and leads to inconsistency between plausible constraints on credences. We show how Humeans can avoid these contradictions by drawing on metaphysically impossible worlds that are, nevertheless, (...) scientifically possible. One major advantage of our approach is that one single move deals with these both problems, whereas previous Humean approaches to undermining (such as that given by Lewis (1994), Thau (1994), and Hall (1994)) have only addressed the connection between credence and chance. Furthermore, our approach connects more closely with the way we employ stochastic scientific theories. And it’s part of a unified solution to other challenges that the Humean faces. (shrink)

Views which deny that there are necessary connections between distinct existences have often been criticized for leading to inductive skepticism. If there is no glue holding the world together then there seems to be no basis on which to infer from past to future. However, deniers of necessary connections have typically been unconcerned. After all, they say, everyone has a problem with induction. But, if we look at the connection between induction and explanation, we can develop the problem of induction (...) in a way that hits deniers of necessary connections, but not their opponents. The denier of necessary connections faces an `internal' problem with induction -- skepticism about important inductive inferences naturally flows from their position in a way that it doesn't for those who accept necessary connections. This is a major problem, perhaps a fatal one, for the denial of necessary connections. (shrink)

Foreword -- Acknowledgements -- Preface -- 1. Introduction -- 2. The concept of Dharma in Purvamīmāmsā -- 3. Dharma as in Buddhism and Jainism -- 4. Dharma as in Mahabharata -- 5. Dharma : the essential properties of man -- 6. Some problems along with critical remarks -- Bibliography -- Index.

In this discussion note I reply to some criticisms that Marc Lange (2022) has directed at my Humean view of scientific laws (Bhogal, 2020) -- about whether Humean views can make sense of the apparent fact that laws are counterfactually invariant. The key idea of my response is that the Humean should think of their reduction of the laws to the Humean mosaic as closely related to other views where we reduce one domain to another but still allow that (...) the higher-level domain can be `autonomous' of the lower-level in some respects -- like, for example, the view that the special sciences reduce to physics but can still can work autonomously of physics. (shrink)

Some patterns call out for explanation, in the sense that we have a pro tanto reason to reject theories that do not give them an appropriate explanation. I argue that certain modal patterns call out for explanation in this way—and this provides a reason to reject certain theories of modality that fail to explain such patterns. However, I also consider a response to this argument, which claims that the modal patterns do not need explanation. This response might be viable but (...) it involves some substantial commitments about the nature of explanation. (shrink)

Study on the educational thoughts of Mother, 1878-1973, associate of Aurobindo Ghose, 1872-1950, Indic philosopher.

Humeanism – the idea that there are no necessary connections between distinct existences – and Nomic Essentialism – the idea that properties essentially play the nomic roles that they do – are two of the most important and influential positions in the metaphysics of science. Traditionally, it has been thought that these positions were incompatible competitors. We disagree. We argue that there is an attractive version of Humeanism that captures the idea that, for example, mass essentially plays the role that (...) it actually does in the laws of nature. In this paper we consider the arguments that have lead many to conclude that Humeanism cannot be combined with Nomic Essentialism; we identify the weaknesses in these arguments; and we argue in detail that a version of Humeanism based on a variant of the Best System account of laws captures the key intuitions behind nomic essentialism. (shrink)

Abstract:Private land is vitally important to land conservation efforts, but access to private landowners is a challenge for researchers. This paper studies the preferences and concerns of such landowners on the rural-urban fringe of Stafford County, Virginia. Participatory research and interviews with 53 private landowners show that conservation is deeply embedded within key social, moral, cultural, and political contexts, including a divide between long-term and newer residents. Successful conservation requires such social knowledge. It is argued that landowner skepticism about local (...) government points towards joint strategies between local government and partner groups. Land conservation should be framed as an affirmation of—not limitation on—property rights since urban fringe landowners are likely to see such rights as under attack. Conservation also presents an opportunity for community building in rapidly urbanizing areas. (shrink)

This study looks into the role that eye contact plays in helping people to control themselves in social settings and to avoid breaking social norms. Based on previous research, it is likely that eye contact increases prosocial behavior via heightened self-awareness and increased interpersonal synchrony. In our study, we propose that eye contact can also support constructive social behavior by causing people to experience heightened embarrassment when they are breaking social norms. We tested this in a lab experiment in which (...) participants read insults at the experimenter. In the experimental condition, participants maintained eye contact with the experimenter. In the control condition, the experimenter did not maintain eye contact. We measured embarrassment with a self-report measure, heart rate to capture arousal, and two observational indicators of embarrassment. In line with our hypotheses, having eye contact during norm breaking behavior as compared to no eye contact led to a stronger increase in self-reported embarrassment, a higher heart rate as well as more hesitation and more laughter. We conclude that eye contact does indeed lead to more embarrassment, while breaking social norms. This implies that eye contact gives people the power to punish norm breaking in others by inducing an aversive emotional experience. (shrink)

What are the challenges of turning data subjects into research participants—and how can we approach this task responsibly? In this paper, we develop a methodology for studying the lived experiences of people who are subject to automated scoring systems. Unlike most media technologies, automated scoring systems are designed to track and rate specific qualities of people without their active participation. Credit scoring, risk assessments, and predictive policing all operate obliquely in the background long before they come to matter. In doing (...) so, they constitute a problem not only for those subject to these systems but also for researchers who try to study their experience. Specifically, we identify three challenges that are distinct to studying experiences of automated scoring: limited awareness, embeddedness, and ongoing inquiry. Starting from the observation that coming to terms with one's position as a data subject constitutes a form of learning in its own right, we propose a research strategy called critical companionship. Originally articulated in the context of nursing research, critical companionship invites us to accompany a data subject over time, paying critical attention to how the participant's and the researcher's inquiries complicate and constitute each other. We illustrate the strengths and limitations of this methodology with materials from a recent study we conducted about people's credit repair practices and sketch a set of sensibilities for studying contemporary scoring systems from the margins. (shrink)

A historical investigation of the exclusion of Africa and Asia from modern histories of philosophy.

Why do we value higher-level scientific explanations if, ultimately, the world is physical? An attractive answer is that physical explanations often cite facts that don’t make a difference to the event in question. I claim that to properly develop this view we need to commit to a type of deterministic chance. And in doing so, we see the theoretical utility of deterministic chance, giving us reason to accept a package of views including deterministic chance.

Explaining the supervenience of the moral on the natural is, perhaps, the central metaphysical challenge for the non-naturalist. However, Scanlon (2014) and Fogal and Risberg (2020) have developed a strategy which purports to explain supervenience rather simply. Fogal and Risberg call it the 'Divide and Conquer' strategy. The key idea is to postulate explanatory moral principles linking the natural and the moral. The moral principles are metaphysically necessary, so trivially supervene on the natural. All other moral facts are determined by (...) the necessary moral principles and the natural facts, so they supervene on the natural too. -/- I argue that there are two versions of the Divide and Conquer strategy and both fail. The first strategy doesn’t give an adequate explanation of supervenience because it doesn't properly identify what makes a difference to the holding of supervenience. The second perhaps does give an adequate explanation of supervenience, but only by introducing something similarly puzzling that needs explanation. -/- Consequently, non-naturalists need additional metaphysical machinery to develop their view -- just appealing to moral principles or metaphysical laws won't do the job. (shrink)

The translation of the Guru Granth Sahib (GGS), or Sikh ‘scripture’, within the discourse of (European) colonial/modernity was enacted by the use of hermeneutics—which oversaw the shift from the openness of praxis to the closure of representation and knowledge. Such a shift demoted certain indigenous interpretive frames, wherein the GGS is assumed to enunciate an excess that far transcends the foreign demand to fix the text’s ‘call’ into singular meanings (beyond time), but rather transforms the hermeneutic desire into a process (...) of learning (Sikhi) through multiple meanings (in time). Thus the GGS is not translated according to a particular life-world, but actively transforms the life-world of those that respond to its excessive call. How should hermeneutics be reformed in this case? If the GGS as text demands interpretation, then the text as Guru demands engagement, and together they would necessarily call forth a radicalization of hermeneutics via a certain poetic reticence to all philosophical messengers. (shrink)

Putative counterexamples to the Principle of Identity of Indiscernibles (PII) are notoriously inconclusive. I establish ground rules for debate in this area, offer a new response to such counterexamples for friends of the PII, but then argue that no response is entirely satisfactory. Finally, I undermine some positive arguments for PII.

Mental health research and care in the twenty first century faces a series of conceptual and ethical challenges arising from unprecedented advances in the neurosciences, combined with radical cultural and organisational change. The Oxford Textbook of Philosophy of Psychiatry is aimed at all those responding to these challenges, from professionals in health and social care, managers, lawyers and policy makers; service users, informal carers and others in the voluntary sector; through to philosophers, neuroscientists and clinical researchers. Organised around a series (...) of case studies in five key topic areas - concepts of disorder, the philosophical history of psychopathology, philosophy of science, ethics and philosophical value theory, and philosophy of mind - the book provides a detailed introduction to the field and a framework for study and skill development. Each case study is supported by selected readings from both philosophy and mental health, thinking skills exercises, self-test questions, key learning points and detailed guides to further reading. There is an introduction for philosophers to classification and descriptive psychopathology, and for practitioners to philosophical methods (including logic). The philosophical topics covered include philosophical methods (analytic and Continental); phenomenology, hermeneutics and existentialism, logical empiricism and its successors; idealism and realism; reasons and causes; and modern theories of mind and brain, free will and personal identity. Topics from mental health include psychiatry and 'anti-psychiatry'; Jaspers' psychopathology and the new neurosciences; the future of psychiatric classifications; strengths-based approaches, recovery practice, social inclusion and diversity; and key topics in psychopathology, such as delusion, autism, disorders of volition, thought insertion and other experiences in schizophrenia. The Oxford Textbook of Philosophy of Psychiatry aims to secure the skills-base of the discipline by bringing philosophers closer to the realities of practice in mental health, and mental health practitioners closer to the resources of philosophy as a partner to the sciences in responding to the challenges of twenty-first century mental health and social care. (shrink)

This book is a defense of modal realism; the thesis that our world is but one of a plurality of worlds, and that the individuals that inhabit our world are only a few out of all the inhabitants of all the worlds. Lewis argues that the philosophical utility of modal realism is a good reason for believing that it is true.

How (Not) to Be Secular is what Jamie Smith calls "your hitchhiker's guide to the present" -- it is both a reading guide to Charles Taylor's monumental work A Secular Age and philosophical guidance on how we might learn to live in our times. Taylor's landmark book A Secular Age (2007) provides a monumental, incisive analysis of what it means to live in the post-Christian present -- a pluralist world of competing beliefs and growing unbelief. Jamie Smith's book is a (...) compact field guide to Taylor's insightful study of the secular, making that very significant but daunting work accessible to a wide array of readers. Even more, though, Smith's How (Not) to Be Secular is a practical philosophical guidebook, a kind of how-to manual on how to live in our secular age. It ultimately offers us an adventure in self-understanding and maps out a way to get our bearings in today's secular culture, no matter who "we" are -- whether believers or skeptics, devout or doubting, self-assured or puzzled and confused. This is a book for any thinking person to chew on. (shrink)

Philosophy has much to offer psychiatry, not least regarding ethical issues, but also issues regarding the mind, identity, values, and volition. This has become only more important as we have witnessed the growth and power of the pharmaceutical industry, accompanied by developments in the neurosciences. However, too few practising psychiatrists are familiar with the literature in this area. -/- The Oxford Handbook of Philosophy and Psychiatry offers the most comprehensive reference resource for this area ever published. It assembles challenging and (...) insightful contributions from key philosophers and others to the interactive fields of philosophy and psychiatry. Each contributions is original, stimulating, thorough, and clearly and engagingly written - with no potentially significant philosophical stone left unturned. Broad in scope, the book includes coverage of several areas of philosophy, including philosophy of mind, science, and ethics. For philosophers and psychiatrists, The Oxford Handbook of Philosophy and Psychiatry is a landmark publication in the field - one that will be of value to both students and researchers in this rapidly growing area. (shrink)

Neoplatonic allegorical interpretation expounds how literary texts present philosophical ideas in an enigmatic and coded form, offering an alternative path to the divine truths. The Neoplatonist Porphyry’s _On the Cave of the Nymphs_ is one of the most significant allegorical interpretation handed down to us from Antiquity. This monograph, exclusively dedicated to the analysis of _On the Cave of Nymphs_, demonstrates that Porphyry interprets Homer’s verse from Odyssey 13.102-112 to convey his philosophical thoughts, particularly on the material world, relationship between (...) soul and body and the salvation of the soul through the doctrines of Plato and Plotinus. The Homeric cave of the nymphs with two gates is a station where the souls descend into genesis and ascend to the intelligible realm. Porphyry associates Odysseus’ long wanderings with the journey of the soul and its salvation from the irrational to rational through escape from all toils of the material world. (shrink)

DaB fUr die Entwicklung der Phanomenologie Husserls nicht zuletzt auch,wissenschaftstheoretische' Motive ausschlaggebend waren, ist hinreichend bekannt. Umso mehr verwundert es, daB die Husserl-Rezeption sich diese Motive nur selten zueigen gemacht hat. Zwar sind in einer Reihe von Einzel­ wissenschaften, wie in der Literaturwissenschaft, der Sozialwissenschaft und besonders auch der Psychologie, phanomenologische Motive wirksam gewor­ den. Versuche einer ausdriicklichen wissenschaftskritischen Anwendung der Husserlschen Philosophie auf einzelwissenschaftliehe Theorien jedoch, wie sie z.B. Alfred Schiitz in seinem friihen Werk zur phanomenologischen Grundlegung der "verstehenden (...) Soziologie"l ansatzweise unternommen hat, sind rar. Freilich ging auch Husserl hier nieht eben mit gutem Beispiel voran. Auch er selbst hat seine wissenschaftstheoretische Programmatik nirgends einer ernsthaften Bewahrungsprobe unterzogen. Die vorliegende Untersuchung will diese Frage einer wissenschaftstheore­ tischen Anwendbarkeit der transzendentalen Phiinomenologie paradigmatisch im Hinblick auf die Problemstellungen der Geschiehtswissenschaft iiberprii­ fen. Was also kann die Phanomenologie fUr die Historik leisten? DaB sieh fiir eine solche Absieht gerade die geschichtstheoretischen Perspektiven in Hus­ serls Werk anbieten, hat vor allem zwei Griinde. (shrink)

This chapter provides an introduction to higher-order metaphysics as well as to the contributions to this volume. We discuss five topics, corresponding to the five parts of this volume, and summarize the contributions to each part. First, we motivate the usefulness of higher-order quantification in metaphysics using a number of examples, and discuss the question of how such quantifiers should be interpreted. We provide a brief introduction to the most common forms of higher-order logics used in metaphysics, and indicate a (...) number of questions which can be raised in such systems using logical vocabulary alone. Using a further example, we return to applications of higher-order logics in metaphysics. We also mention key developments in the history of higher-order logic as it pertains to metaphysics. Finally, we mention certain arguments which have been raised against the use of higher-order logic, and some ways of responding to them. (shrink)